A young girl named Kristen (Amber Heard) awakens in a psychiatric hospital after setting a farmhouse ablaze, and finds herself stalked by a malevolent ghost in this psychological shocker from celebrated horror director John Carpenter (Halloween). Badly battered and seemingly stricken with amnesia, Kristen forges a fragile friendship with fellow patients Sarah (Danielle Panabaker), Iris (Lyndsy Fonseca), Emily (Mamie Gummer), and Zoey (Laura-Leigh) as her compassionate therapist, Dr. Stringer (Jared Harris), works to uncover the source of her mysterious condition. Later, at night, when the lights in her remote ward go dim, Kristen is confronted by an imposing phantom that seems intent on dragging her screaming into the darkness. Eventually, the other girls in the ward begin to vanish, one by one. Now, the harder Kristen fights to avoid falling prey to her shadowy pursuer, the more convinced she becomes that no patient who's checked in to North Bend Psychiatric Hospital ever comes out alive.