1 Gas Chromatography-Mass Spectrometry of Prostaglandins. - I. Introduction. - II. Mass Spectrometry Systems for Prostaglandin Analysis. - III. Methods of Extraction and Chromatography. - IV. Biological Applications. - V. References. - Note Added in Proof. - 2 Prostaglandin Biosynthesis and Metabolism as Measured by Radioimmunoassay. - I. Introduction. - II. Serological Specificities of the Prostaglandin Immune Systems. - III. Prostaglandin Synthetase. - IV. Prostaglandin E 9-Ketoreductases. - V. 15-Hydroxyprostaglandin Dehydrogenases. - VI. Prostaglandin ?13-Reductase. - VII. PGE Dehydrase PGA Isomerase and PGC Isomerase. - VIII. Regulation of PGE and PGF Levels. - IX. References. - Note Added in Proof. - 3 The Endocrine System: Interaction of Prostaglandins with Adenylyl Cyclase-Cyclic AMP Systems. - I. Introduction. - II. Thyroid. - III. Pituitary. - IV. Pancreas. - V. Adrenal. - VI. Ovaries. - VII. References. - 4 Induction of Labor with Prostaglandins. - I. Historical Background. - II. Induction of Labor with Intravenous Prostaglandins. - III. Other Routes of Administration. - IV. Conclusions. - V. References. - 5 Cardiovascular Responses to the Prostaglandin Precursors. - I. Introduction. - II. Blood Pressure. - III. Cardiac Effects. - IV. Renal Circulation. - V. Pulmonary Circulation. - VI. Other Regional Circulations. - VII. Platelets 141 VIII Summary. - IX. References. - 6 Role of Prostaglandins in Fever and Temperature Regulation. - I. Introduction. - A. Temperature Regulation B. Fever 148. - II. Role of PGs in Fever. - III. PG Synthesis in Brain during Fever. - IV. Difficulties with the PG Hypothesis. - V. PGs in Normal Temperature Regulation. - VI. Summary of the Existing Evidence. - VII. Addendum. - VIII. References. - 7 Prostaglandins and the Lung. - I. Introduction. - II. Prostaglandin Content andSynthesis in the Lung. - III. Catabolism and Uptake of Prostaglandins in the Lung. - IV. Release of Prostaglandins from the Lung. - V. Bronchopulmonary Effects of Prostaglandins. - VII. Summary and Conclusions. - VIII. References. - Note Added in Proof. - 8 Prostaglandins and the Digestive System. - I. Introduction. - II. Salivary Glands. - III. Esophagus. - IV. Stomach. - VI. Bile and Pancreatic Secretion. - VII. Cytoprotection by Prostaglandins. - VIII. References. - 9 Prostaglandins and Renal Function or A Trip down the Rabbit Hole. - I. Introduction. - II. Prostaglandin Synthesis and Metabolism. - III. Role of Prostaglandins in the Control of Renal Blood Flow. - IV. Role of Prostaglandins in Salt and Water Homeostasis. - V. Conclusion. - VI. References. - Note Added in Proof. - 10 Prostaglandins and Cancer. - I. Introduction. - II. Prostaglandin Synthesis by Tumors and Its Effects on Tumor Cell Replication. - III. Prostaglandins Bone Resorption and Hypercalcemia. - IV. Conclusions. - V. References. Language: English