I Introduction. - 1 The Ponce de Leon Trail Today. - II Aging in Cells and their Molecules. - 2 Cell Aging: A Model System Approach. - 3 Is Limited Cell Proliferation the Clock That Times Aging?. - 4 Molecular Biology of Aging. - III Aging in Plants and Lower Animals. - 5 Cellular and Metabolic Aspects of Senescence in Higher Plants. - 6 The Biological Significance of Death in Plants. - 7 Aging in Lower Animals. - IV Aging in Humans and Other Mammals. - 8 Exercise and Aging. - 9 Diet and Nutrient Needs in Old Age. - 10 Nutritional Regulation of Longevity. - 11 Consequences of Alcohol and Other Drug Use in the Aged. - 12 Physical Changes of the Aging Brain. - 13 Aging and Immune function. - 14 Genes and Aging. - 15 The Dilemma of Aging Parents: Increased Risk of Genetically Abnormal Offspring. - V Hormones and Aging. - 16 Endocrinology and Aging. - 17 Hormone Replacement in the Aged: Proceed with Care. - 18 Altered Biochemical Responsiveness and Hormone Receptor Changes during Aging. - 19 The Brain and Aging. - VI Aging in Perspective. - 20 Evolutionary Biology of Senescence. - 21 The Origin Evolution Nature and Causes of Aging. Language: English