I. General Biochemistry of NOSs and Cellular Actions of NO. - 1. The Biological Chemistry of NO. - 2. Role of NO and Nitrogen Intermediates in Regulation of Cell Functions. - 3. Nitric Oxide Synthases and Their Cofactors. - 4. Regulation of the NOS Gene Family. - 5. Role of NO in Cell Locomotion. - II. Renal Expression of NOSs and Production of NO. - 6. Metabolic Pathways and Cycles of L-Arginine Synthesis and Utilization. - 7. Distribution of NOSs in the Kidney. - III. NO and the Regulation of Renal Hemodynamics. - 8. Vascular Effects of NO. - 9. Role of NO in the Function of the Juxtaglomerular Apparatus. - 10. NOS in Mesangial Cells: Physiological and Pathophysiological Roles. - 11. Tubuloglomerular Feedback and Macula Densa-Derived NO. - 12. NO and the Renin System. - 13. NO and the Medullary Circulation. - IV. Role of NO system in Renal Pathophysiology. - 14. NO in Septic Shock. - 15. NO and Glomerulonephritis. - 16. NO in Acute Renal Failure. - 17. NO in Diabetic Nephropathy. - 18. NO and Hypertension. - 19. NO in Normal and Preeclamptic Pregnancy. - 20. Sickle Cell Disease and NO. - 21. A Putative Role of NO and Oxidant Injury in the Pathogenesis of Hemolytic Uremic Syndrome. - 22. Role of NO in Urinary Tract Infections. - 23. Role of the NO System in Urinary Tract Obstruction. Language: English