Pycnogenol®100 mg, 60 vegetarian capsulesItem Catalog Number: 01637EUPycnogenol® French Maritime Pine Bark Extract is a time-tested anti-aging solution. This natural plant extract contains procyanidins, bioflavonoids, and other beneficial molecules that help the body fight five processes associated with premature aging. Forty years of studies on Pycnogenol® have helped validate its powerful anti-aging properties.Benefits at a GlanceSupports the body’s defenses against 5 mechanisms of premature agingPatented and standardized natural botanical extractForty years of clinical testingSupports healthy cell membrane and DNA functionModulates inflammatory factors through normal mechanismsSupports healthy antioxidant function and cell metabolismComprehensive Anti-Aging PowerThe constituents in Pycnogenol® have a synergistic effect against factors associated with premature aging, working together to:Promote the integrity and normal characteristics of cell membranes.1-4Support healthy DNA function through enhanced antioxidant activity and other potential mechanisms.5-8Promote a healthy inflammatory response through normal modulation of cytokine molecules.9-12Fight oxidative stress by encouraging healthy and normal function of antioxidant systems that help inhibit free radical activity and protect DNA.13-17Encourage healthy cellular metabolism of sugar, healthy blood sugar levels, normal absorption of sugar in the intestine, and post-meal blood sugar levels already within the normal range.18-26This is truly a one-stop formula that can help you beat Father Time at his own game. Add Pycnogenol® to your anti-aging regimen today.Supplement FactsServing Size 1 vegetarian capsuleAmount per day (2 capsules)Pycnogenol® dried French Maritime pine extract (bark) [std. to 65% procyanidins]200 mgIngredients: Bulking agent (microcrystalline cellulose/cellulose gel), maritime pine bark extract (Pinus pinaster Aiton), capsule (hydroxypropyl methyl cellulose), anti-caking agents (fatty acids, silicon dioxide [nano])Non-GMOPycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents. Supported by over 40 years of research.Dosage and UseTake one (1) capsule once or twice daily, with or without food, or as recommended by a healthcare practitioner.WarningsKEEP OUT OF REACH OF CHILDRENDO NOT EXCEED RECOMMENDED DOSEDo not purchase if outer seal is broken or damaged.When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.Gen Physiol Biophys. 2004 Mar;23(1):39-51.Phytother Res. 2008 Mar;22(3):384-8.Biol Pharm Bull. 2000 Jun;23(6):735-7.Phytother Res. 2004 Mar;18(3):244-6.Fitoterapia. 2010 Oct;81(7):724-36.Drug Dev Ind Pharm. 1998 Feb;24(2):139-44.Free Radic Res. 2006 Sep;40(9):1003-10.Phytother Res. 2005 Mar;19(3):262.Photochem Photobiol. 2004 Feb;79(2):193-8.Free Radic Biol Med. 2012 Feb 15;52(4):765-74.J Inflamm (Lond). 2006 Jan 27;3:1.Food Chem Toxicol. 2011 Sep;49(9):2196-201.Int J Clin Pharmacol Ther. 2002 Apr;40(4):158-68.Redox Rep. 2006;11(4):163-72.J Psychopharmacol. 2008 Jul;22(5):553-62.Redox Rep. 2008;13(6):271-6.Lipids. 2002 Oct;37(10):931-4.Diabetes Care. 2004 Mar;27(3):839.Res Pharm Sci. 2011 Jan;6(1):1-11.Chinese Pharmacological Bulletin, 2003; 19(4):437-440.Nutr Res. 2008 May;28(5):315-20.Phytother Res. 2010 Aug;24(8):1242-9.Life Sci. 2004 Oct 8;75(21):2505-13.Chem Biol Interact. 2010 Jul 30;186(2):219-27.Phytother Res. 2013 Oct;27(10):1572-8.Phytother Res. 2015 Jul;29(7):949-68.