MSM1000 mg, 100 capsulesItem Catalog Number: 00451EUMSM (methylsulfonylmethane or dimethylsulfone) is a sulfur-containing molecule found in various plants and some body tissues.1-5 MSM is a vital building block of joints, cartilage, skin, hair and nails. It is an efficient source of the sulfur that is used by many of the body’s structural molecules.5 Some peer-reviewed clinical research in the U.S. has shown MSM is safe and effective in increasing joint comfort and supporting a normal range of motion.6-11Supplement FactsServing Size 3 capsulesServings Per Container 33Amount Per ServingMethylsulfonylmethane3000 mgOther ingredients: gelatin, vegetable stearate.Non-GMODosage and UseTake three (3) capsules once or twice daily with or without food, or as directed by a healthcare practitioner.WarningsKEEP OUT OF REACH OF CHILDRENDO NOT EXCEED RECOMMENDED DOSEDo not purchase if outer seal is broken or damaged.When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.J Agric Food Chem. 1981 Sep-Oct;29(5):1089-91.J Biol Chem 1940;134:781-2.Arch Biochem Biophys 1966;113:251-2.Toxicol Lett 2001;123:169-177.Altern Med Rev. 2003 Nov;8(4):438-41.Osteoarthritis Cartilage. 2008 Nov;16(11):1277-88.Osteoarthritis and Cartilage 2006;14:286-94.BMC Complement Altern Med. 2011 Jun 27;11:50.Clin Drug Invest 2004; 24:353-63.Iran J Pharmacol Ther 2004;3:61-5.Evid Based Complement Alternat Med. 2011;2011:528403.