Full PotencyIn Foil Blister PackpH SensitiveFood GradeEnteroGuard® CoatingS-Adenosyl Methionine200 mg (Net Yield) SAM-e from 400 mg SAM-e tosylate DisulfateHighest Concentration of Active S,S FormEnteric-Coated TabletsNet Yield -200 Mg SAM-eGluten FreeVeganDietary Supplement Supports: Joint StrengthBrain Metabolism and MoodLiver Function Jarrow Formulas® SAM-e 200 provides a full 200 mg SAM-e (net yield) from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. Contains More of the Active S,S Form Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAM-e, the highest active level available. SAMe supports: Joint Strength SAME supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGS, such as glucosamine sulfate and chondroitin sulfate. Brain Metabolism SAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes and precursor to acetylcholine, as well as neurotransmitters such as dopamine, norepinephrine, and serotonin, and has been shown to have a positive effect on mood. Liver SAMe metabolism supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification. EnteroGuard® is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resist stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.